Cyclo (RGDfK)

Description:

An RGD tumor-targeting peptide, which binds to αvβ3 receptors.

Sequence:

c(RGDfK)

General

References

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Name	Cyclo (RGDfK)
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	c(RGDfK)
Three Letter Code	Cyclo(-Arg-Gly-Asp-D-Phe-Lys)
Molecular Weight	603.680
Application	Adhesion Molecules & Extracellular Matrix ProteinsCancer ResearchRegenerative Medicine

Haedicke, Katja, et al. "Multifunctional calcium phosphate nanoparticles for combining near-infrared fluorescence imaging and photodynamic therapy." Acta biomaterialia 14 (2015): 197-207.

Vilchis-Juárez, Andrea, et al. "Molecular targeting radiotherapy with cyclo-RGDFK (C) peptides conjugated to 177Lu-labeled gold nanoparticles in tumor-bearing mice." Journal of biomedical nanotechnology 10.3 (2014): 393-404.

Ocampo-García, Blanca E., et al. "Design and biological evaluation of 99mTc-N2S2-Tat (49–57)-c (RGDyK): A hybrid radiopharmaceutical for tumors expressing α (v) β (3) integrins." Nuclear medicine and biology 40.4 (2013): 481-487.

Hao, Guiyang, et al. "Cyclization of RGD peptide sequences via the macrocyclic chelator DOTA for integrin imaging." Dalton Transactions 41.46 (2012): 14051-14054.

Wildt, Bridget, Denis Wirtz, and Peter C. Searson. "Triggering cell detachment from patterned electrode arrays by programmed subcellular release." Nature protocols 5.7 (2010): 1273.