Integrin Binding Peptide

Description:

This is fibronectin derived, integrin-binding peptide. It may be used for PEG hydrogel preparation.

Sequence:

Ac-GCGYGRGDSPG-NH2

General

References

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Name	Integrin Binding Peptide
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	Ac-GCGYGRGDSPG-NH2
Three Letter Code	Ac-{Gly}{Cys}{Gly}{Tyr}{Gly}{Arg}{Gly}{Asp}{Ser}{Pro}{Gly}-NH2
Molecular Weight	1066.100
Application	Adhesion Molecules & Extracellular Matrix ProteinsCancer ResearchRegenerative Medicine

Raeber, G. P., M. P. Lutolf, and J. A. Hubbell. "Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration." Biophysical journal89.2 (2005): 1374-1388.

Holloway, Julianne L., et al. "Modulating hydrogel crosslink density and degradation to control bone morphogenetic protein delivery and in vivo bone formation." Journal of controlled release 191 (2014): 63-70.

Griffin, Donald R., et al. "Synthesis of photodegradable macromers for conjugation and release of bioactive molecules." Biomacromolecules 14.4 (2013): 1199-1207.

Raeber, G. P., M. P. Lutolf, and J. A. Hubbell. "Molecularly engineered PEG hydrogels: a novel model system for proteolytically mediated cell migration." Biophysical journal 89.2 (2005): 1374-1388.

Lutolf, Matthias P., et al. "Repair of bone defects using synthetic mimetics of collagenous extracellular matrices." Nature biotechnology 21.5 (2003): 513-518.