H-D-Arg-Gly-Asp-Trp-OH

Description:

This fragment inhibits platelet aggregation and adhesion to fibrinogen and fibrin.

Sequence:

{D-Arg}GDW

General

References

Comments (0)

Name	H-D-Arg-Gly-Asp-Trp-OH
Category	Fibronectin Fragments, RGD Peptides
One Letter Code	{D-Arg}GDW
Three Letter Code	{D-Arg}{Gly}{Asp}{Trp}
Molecular Weight	532.560
Application	Adhesion Molecules & Extracellular Matrix ProteinsHematologyRegenerative Medicine

Vella, Fanny, et al. "A recombinant chimeric epidermal growth factor-like module with high binding affinity for integrins." Journal of Biological Chemistry 278.22 (2003): 19834-19843.

Lisman, Ton, et al. "Recombinant factor VIIa enhances deposition of platelets with congenital or acquired αIIbβ3 deficiency to endothelial cell matrix and collagen under conditions of flow via tissue factor–independent thrombin generation." Blood, The Journal of the American Society of Hematology 101.5 (2003): 1864-1870.

Beguin, S., et al. "Fibrin-dependent platelet procoagulant activity requires GPIb receptors and von Willebrand factor." Blood, The Journal of the American Society of Hematology 93.2 (1999): 564-570.