Temporin A, amide

Description:

Temporin A is a highly hydrophobic antimicrobial peptide derived from the frog Rana temporaria. This peptide could regulate microbial membrane permeability and exhibits activity against gram-positive bacteria.

Sequence:

FLPLIGRVLSGIL-NH2

General

References

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Name	Temporin A, amide
Category	Antimicrobial and Related Peptides
One Letter Code	FLPLIGRVLSGIL-NH2
Three Letter Code	{Phe}{Leu}{Pro}{Leu}{Ile}{Gly}{Arg}{Val}{Leu}{Ser}{Gly}{Ile}{Leu}-NH2
Molecular Weight	1396.800
Application	Temporins

Giacometti, Andrea, et al. "In vitro activity and killing effect of temporin A on nosocomial isolates of Enterococcus faecalis and interactions with clinically used antibiotics." Journal of Antimicrobial Chemotherapy 55.2 (2005): 272-274.

Rosenfeld, Yosef, et al. "A synergism between temporins toward Gram-negative bacteria overcomes resistance imposed by the lipopolysaccharide protective layer." Journal of Biological Chemistry 281.39 (2006): 28565-28574.

Ye, R. D., et al. "Pharmacol. Rev." (2009).