Exendin-3

Description:

A member of the glucagon superfamily,

Sequence:

HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH₂
  • General
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  • Name Exendin-3
    Category Exendins and Fragments
    One Letter Code HSDGTFTSDLSKQMEEEAVRLFIEWLKNGGPSSGAPPPS-NH₂
    Three Letter Code {His}{Ser}{Asp}{Gly}{Thr}{Phe}{Thr}{Ser}{Asp}{Leu}{Ser}{Lys}{Gln}{Met}{Glu}{Glu}{Glu}{Ala}{Val}{Arg}{Leu}{Phe}{Ile}{Glu}{Trp}{Leu}{Lys}{Asn}{Gly}{Gly}{Pro}{Ser}{Ser}{Gly}{Ala}{Pro}{Pro}{Pro}{Ser}-NH₂
    Molecular Weight 4202.630
    Application Diabetes
    Thum, A., et al. "Endoproteolysis by isolated membrane peptidases reveal metabolic stability of glucagon-like peptide-1 analogs, exendins-3 and-4." Experimental and clinical endocrinology & diabetes 110.03 (2002): 113-118.
    Eng, John, et al. "Isolation and characterization of exendin-4, an exendin-3 analogue, from Heloderma suspectum venom. Further evidence for an exendin receptor on dispersed acini from guinea pig pancreas." Journal of Biological Chemistry 267.11 (1992): 7402-7405.
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