Helodermin

Description:

Among all known VIP-related peptides, helodermin was the most potent in stimulating cAMP production by NCI-H345 cell line.

Sequence:

HSDAIFTQQYSKLLAKLALQKYLASILGSRTSPPP-NH₂

General

References

Comments (0)

Name	Helodermin
Category	Exendins and Fragments
One Letter Code	HSDAIFTQQYSKLLAKLALQKYLASILGSRTSPPP-NH₂
Three Letter Code	His}{Ser}{Asp}{Ala}{Ile}{Phe}{Thr}{Glu}{Glu}{Tyr}{Ser}{Lys}{Leu}{Leu}{Ala}{Lys}{Leu}{Ala}{Leu}{Gln}{Lys}{Tyr}{Leu}{Ala}{Ser}{Ile}{Leu}{Gly}{Ser}{Arg}{Thr}{Ser}{Pro}{Pro}{Pro}-NH2
Molecular Weight	3843.490
Application

Dejda, Agnieszka, et al. "Cyclic AMP formation in chicken brain: effect of vasoactive intestinal peptide, peptide histidine-isoleucine (PHI), and some PHI-related peptides." Polish journal of pharmacology 55.5 (2003): 747-752.

Luis, José, and Sami I. Said. "Characterization of VIP-and helodermin-preferring receptors on human small cell lung carcinoma cell lines." Peptides 11.6 (1990): 1239-1244.

Hoshino, M. "Y. Katsumaru, A. Vandermeers. M.-C. Vandermeers-Piro. P. Robberecht, J. Christophe and N. Yanaihara. Primary structure of helodermin, a VIP-secretin-like peptide isolated from Gila monster venom." FEBS Lett 178 (1984): 233-239.