Ranalexin

Description:

Ranalexin is an amphibian antimicrobial peptide isolated from the skin of the American bullfrog, Rana catesbeiana. It contains disulfide bond at position 14 and 20 of Cys.

Sequence:

FLGGLIKIVPAMICAVTKKC (Disulfide bridge: 14-20)

General

References

Comments (0)

Name	Ranalexin
Category	Antimicrobial and Related Peptides
One Letter Code	FLGGLIKIVPAMICAVTKKC (Disulfide bridge: 14-20)
Three Letter Code	{Phe}{Leu}{Gly}{Gly}{Leu}{Ile}{Lys}{Ile}{Val}{Pro}{Ala}{Met}{Ile}{Cys}{Ala}{Val}{Thr}{Lys}{Lys}{Cys} (Disulfide bridge: 14-20) (Disulfide bridge: 14-20)
Molecular Weight	2103.730
Application	Antimicrobial & Antiviral Peptides

Desbois, Andrew P., Curtis G. Gemmell, and Peter J. Coote. "In vivo efficacy of the antimicrobial peptide ranalexin in combination with the endopeptidase lysostaphin against wound and systemic meticillin-resistant Staphylococcus aureus (MRSA) infections." International journal of antimicrobial agents 35.6 (2010): 559-565.

Giacometti, A., et al. "In vitro activities of membrane-active peptides alone and in combination with clinically used antimicrobial agents against Stenotrophomonas maltophilia." Antimicrobial agents and chemotherapy 44.6 (2000): 1716-1719.

Clark, Douglas P., et al. "Ranalexin. A novel antimicrobial peptide from bullfrog (Rana catesbeiana) skin, structurally related to the bacterial antibiotic, polymyxin." Journal of Biological Chemistry 269.14 (1994): 10849-10855.