Suc-Val-Pro-Phe-pNA

Description:

Sensitive substrate for mammalian chymotrypsin and chymotrypsin-like enzymes

Sequence:

Succinylation-VPF-p-Nitroanilide

General

References

Comments (0)

Name	Suc-Val-Pro-Phe-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-VPF-p-Nitroanilide
Three Letter Code	Succinylation-{Val}{Pro}{Phe}-p-Nitroanilide
Molecular Weight	581.630
Application

Jakobsen, Rasmus Kragh, et al. "Fluorescently labeled inhibitors detect localized serine protease activities in Drosophila melanogaster pole cells, embryos, and ovarian egg chambers." Histochemistry and cell biology 123.1 (2005): 51-60.

Powers, James C., et al. "Mammalian chymotrypsin-like enzymes. Comparative reactivities of rat mast cell proteases, human and dog skin chymases, and human cathepsin G with peptide 4-nitroanilide substrates and with peptide chloromethyl ketone and sulfonyl fluoride inhibitors." Biochemistry 24.8 (1985): 2048-2058.

Tanaka, Takumi, et al. "Human leukocyte cathepsin G. Subsite mapping with 4-nitroanilides, chemical modification, and effect of possible cofactors." Biochemistry 24.8 (1985): 2040-2047.