Suc-Leu-Leu-Val-Tyr-pNA

Description:

chromogenic substrate analog to the proteasome substrate Suc-LLVY-AMC.

Sequence:

Succinylation-LLVY-p-Nitroanilide
  • General
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  • Name Suc-Leu-Leu-Val-Tyr-pNA
    Category Enzyme Substrates and Inhibitors
    One Letter Code Succinylation-LLVY-p-Nitroanilide
    Three Letter Code Succinylation-{Leu}{Leu}{Val}{Tyr}-p-Nitroanilide
    Molecular Weight 726.830
    Application
    Roy, Ananya, et al. "Mast cell chymase degrades the alarmins heat shock protein 70, biglycan, HMGB1, and interleukin-33 (IL-33) and limits danger-induced inflammation." Journal of Biological Chemistry 289.1 (2014): 237-250.
    Ahooghalandari, Parvin, et al. "Mutations in Arg143 and Lys192 of the human mast cell chymase markedly affect the activity of five potent human chymase inhibitors." PloS one 8.6 (2013).
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