Suc-Gly-Pro-AMC

Description:

The highly sensitive, fluorogenic substrate Suc-GP-AMC is suitable for the determination of prolyl endopeptidase (postproline cleaving enzyme) activity.

Sequence:

Succinylation-GF-AMC

General

References

Comments (0)

Name	Suc-Gly-Pro-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-GF-AMC
Three Letter Code	Succinylation-{Gly}{Pro}-AMC
Molecular Weight	429.430
Application

Da Zhou, Bing-Hang Li, et al. "Prolyl oligopeptidase inhibition attenuates steatosis in the L02 human liver cell line." PloS one 11.10 (2016).

Roda, Mojtaba Abdul, et al. "Targeting prolyl endopeptidase with valproic acid as a potential modulator of neutrophilic inflammation." PloS one 9.5 (2014).

Venäläinen, Jarkko I., et al. "Binding kinetics and duration of in vivo action of novel prolyl oligopeptidase inhibitors." Biochemical pharmacology 71.5 (2006): 683-692.

Puttonen, Katja A., et al. "A prolyl oligopeptidase inhibitor, Z-Pro-Prolinal, inhibits glyceraldehyde-3-phosphate dehydrogenase translocation and production of reactive oxygen species in CV1-P cells exposed to 6-hydroxydopamine." Toxicology in vitro 20.8 (2006): 1446-1454.