Suc-Ala-Ile-Pro-Phe-pNA

Description:

The chromogenic substrates Suc-AIPF-pNA and Suc-ALPF-Pna are used in a combined assay for measuring the peptidylprolyl isomerases FKBP51 and FKBP52.

Sequence:

Succinylation-AIPF-p-Nitroanilide

General

References

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Name	Suc-Ala-Ile-Pro-Phe-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-AIPF-p-Nitroanilide
Three Letter Code	Succinylation-{Ala}{Ile}{Pro}{Phe}-p-Nitroanilide
Molecular Weight	666.730
Application

Jinwal, Umesh K., et al. "The Hsp90 cochaperone, FKBP51, increases Tau stability and polymerizes microtubules." Journal of Neuroscience 30.2 (2010): 591-599.

Riggs, Daniel L., et al. "Noncatalytic role of the FKBP52 peptidyl-prolyl isomerase domain in the regulation of steroid hormone signaling." Molecular and cellular biology 27.24 (2007): 8658-8669.

Cox, Marc B., et al. "FK506-binding protein 52 phosphorylation: a potential mechanism for regulating steroid hormone receptor activity." Molecular Endocrinology 21.12 (2007): 2956-2967.