Suc-Ala-Phe-Pro-Phe-pNA

Description:

Substrate for FK-506 binding proteins (FKBPs, also called macrophilins) and cyclophilins

Sequence:

Succinylation-AFPF-p-Nitroanilide

General

References

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Name	Suc-Ala-Phe-Pro-Phe-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-AFPF-p-Nitroanilide
Three Letter Code	Succinylation-{Ala}{Phe}{Pro}{Phe}-p-Nitroanilide
Molecular Weight	700.750
Application

Norville, Isobel H., et al. "The structure of a Burkholderia pseudomallei immunophilin–inhibitor complex reveals new approaches to antimicrobial development." Biochemical Journal 437.3 (2011): 413-422.

Erben, Esteban D., et al. "Identification of an atypical peptidyl-prolyl cis/trans isomerase from trypanosomatids." Biochimica et Biophysica Acta (BBA)-Molecular Cell Research 1803.9 (2010): 1028-1037.

Kervinen, Jukka, et al. "Potency variation of small-molecule chymase inhibitors across species." Biochemical pharmacology 80.7 (2010): 1033-1041.

Aumüller, Tobias, et al. "Role of prolyl cis/trans isomers in cyclophilin-assisted Pseudomonas syringae AvrRpt2 protease activation." Biochemistry 49.5 (2010): 1042-1052.

Davis, Tara L., et al. "Structural and biochemical characterization of the human cyclophilin family of peptidyl-prolyl isomerases." PLoS biology 8.7 (2010).