Suc-Ala-Phe-Lys-AMC

Description:

A highly sensitive fluorogenic substrate for plasmin.

Sequence:

Succinylation-AFK-AMC
  • General
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  • Name Suc-Ala-Phe-Lys-AMC
    Category Enzyme Substrates and Inhibitors
    One Letter Code Succinylation-AFK-AMC
    Three Letter Code Succinylation-{Ala}{Phe}{Lys}-AMC
    Molecular Weight 621.690
    Application Hematology
    Ward, Jon R., et al. "Potentiation of TLR4 signalling by plasmin activity." Biochemical and biophysical research communications 341.2 (2006): 299-303.
    Milner, J. M., et al. "Inhibition of furin‐like enzymes blocks interleukin‐1α/oncostatin M–stimulated cartilage degradation." Arthritis & Rheumatism: Official Journal of the American College of Rheumatology 48.4 (2003): 1057-1066.
    Ekici, Özlem Doǧan, et al. "Design, synthesis, and evaluation of aza-peptide Michael acceptors as selective and potent inhibitors of caspases-2,-3,-6,-7,-8,-9, and-10." Journal of medicinal chemistry 49.19 (2006): 5728-5749.
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