Suc-Ala-Ala-Pro-Arg-pNA

Description:

a substrate for wild-type and K188D/D189K trypsins

Sequence:

Succinylation-AAPR-p-Nitroanilide

General

References

Comments (0)

Name	Suc-Ala-Ala-Pro-Arg-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-AAPR-p-Nitroanilide
Three Letter Code	Succinylation-{Ala}{Ala}{Pro}{Arg}-p-Nitroanilide
Molecular Weight	633.660
Application

McLaughlin, Christopher K., et al. "Stable colloidal drug aggregates catch and release active enzymes." ACS chemical biology 11.4 (2016): 992-1000.

Martin, Erik W., et al. "Targeting the membrane-anchored serine protease testisin with a novel engineered anthrax toxin prodrug to kill tumor cells and reduce tumor burden." Oncotarget 6.32 (2015): 33534.

Sisay, Mihiret Tekeste, et al. "Identification of the first low-molecular-weight inhibitors of matriptase-2." Journal of medicinal chemistry 53.15 (2010): 5523-5535.

Yunt, Zeynep, et al. "Cleavage of four carbon− carbon bonds during biosynthesis of the Griseorhodin A spiroketal pharmacophore." Journal of the American Chemical Society 131.6 (2009): 2297-2305.

Kolp, Sonja, et al. "Compatible solutes as protectants for zymogens against proteolysis." Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1764.7 (2006): 1234-1242.