Suc-Ala-Ala-Pro-Ala-pNA

Description:

an excellent substrate for porcine pancreatic elastase. Substrate for α-lytic protease.

Sequence:

Succinylation-AAPA-p-Nitroanilide

General

References

Comments (0)

Name	Suc-Ala-Ala-Pro-Ala-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-AAPA-p-Nitroanilide
Three Letter Code	Succinylation-{Ala}{Ala}{Pro}{Ala}-p-Nitroanilide
Molecular Weight	548.550
Application

Kervinen, Jukka, et al. "Potency variation of small-molecule chymase inhibitors across species." Biochemical pharmacology 80.7 (2010): 1033-1041.

Kervinen, Jukka, et al. "Structural basis for elastolytic substrate specificity in rodent α-chymases." Journal of Biological Chemistry 283.1 (2008): 427-436.

Karlson, Ulrika, et al. "Extended substrate specificity of rat mast cell protease 5, a rodent α-chymase with elastase-like primary specificity." Journal of Biological Chemistry 278.41 (2003): 39625-39631.

Ivanov, Dmitri, William W. Bachovchin, and Alfred G. Redfield. "Boron-11 pure quadrupole resonance investigation of peptide boronic acid inhibitors bound to α-lytic protease." Biochemistry 41.5 (2002): 1587-1590.