Suc-Ala-Ala-Phe-AMC

Description:

A sensitive fluorogenic chymotrypsin substrate. Suc-AAF-MCA has also been used for the chymotrypsin-like activity of the 20S proteasome.

Sequence:

Succinylation-AAF-AMC

General

References

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Name	Suc-Ala-Ala-Phe-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	Succinylation-AAF-AMC
Three Letter Code	Succinylation-{Ala}{Ala}{Phe}-AMC
Molecular Weight	564.600
Application

Poras, Hervé, et al. "New orally active dual enkephalinase inhibitors (DENKIs) for central and peripheral pain treatment." Journal of medicinal chemistry 57.13 (2014): 5748-5763.

Poras, Hervé, et al. "A sensitive fluorigenic substrate for selective in vitro and in vivo assay of leukotriene A4 hydrolase activity." Analytical biochemistry 441.2 (2013): 152-161.

Habisch, Hans-Jörg, et al. "Efficient processing of Alzheimer's disease amyloid-Beta peptides by neuroectodermally converted mesenchymal stem cells." Stem cells and development 19.5 (2010): 629-633.