H-Pro-Phe-Arg-AMC

Description:

A highly sensitive, fluorogenic substrate for plasma as well as pancreatic and urinary kallikreins. Stock solutions of this substrate are best prepared in DMSO.

Sequence:

PFR-AMC

General

References

Comments (0)

Name	H-Pro-Phe-Arg-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	PFR-AMC
Three Letter Code	{Pro}{Phe}{Arg}-AMC
Molecular Weight	575.670
Application	Cardiovascular System & Diseases

Berman, Jonathan M., Ryan G. Awayda, and Mouhamed S. Awayda. "Effects of urine composition on epithelial Na+ channel‐targeted protease activity." Physiological reports 3.11 (2015): e12611.

Portelli, Michael A., et al. "Genome-wide protein QTL mapping identifies human plasma kallikrein as a post-translational regulator of serum uPAR levels." The FASEB Journal 28.2 (2014): 923-934.

Sabotič, Jerica, et al. "Structural basis of trypsin inhibition and entomotoxicity of cospin, serine protease inhibitor involved in defense of Coprinopsis cinerea fruiting bodies." Journal of Biological Chemistry 287.6 (2012): 3898-3907.

Avanzo, Petra, et al. "Trypsin-specific inhibitors from the basidiomycete Clitocybe nebularis with regulatory and defensive functions." Microbiology 155.12 (2009): 3971-3981.

Bubik, Anja, et al. "Cytotoxic and peptidase inhibitory activities of selected non-hepatotoxic cyclic peptides from cyanobacteria." Biological chemistry 389.10 (2008): 1339-1346.

Emami, Nashmil, and Eleftherios P. Diamandis. "Human kallikrein-related peptidase 14 (KLK14) is a new activator component of the KLK proteolytic cascade possible function in seminal plasma and skin." Journal of Biological Chemistry 283.6 (2008): 3031-3041.