Autocamtide - 2 - Related Inhibitory Peptide (AIP); CaMKII Inhibitor, myristoylated

Description:

This is a myristoylated form of Autocamtide-2-Related Inhibitory Peptide (AIP), a highly potent and specific substrate competitive inhibitor of Calmodulin-Dependent Protein Kinase ll (CaMKII).

Sequence:

Myristoyl-KKALRRQEAVDAL

General

References

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Name	Autocamtide - 2 - Related Inhibitory Peptide (AIP); CaMKII Inhibitor, myristoylated
Category	Enzyme Substrates and Inhibitors
One Letter Code	Myristoyl-KKALRRQEAVDAL
Three Letter Code	Myristoyl-{Lys}{Lys}{Ala}{Leu}{Arg}{Arg}{Gln}{Glu}{Ala}{Val}{Asp}{Ala}{Leu}
Molecular Weight	1708.200
Application

Ishida, Atsuhiko, and Hitoshi Fujisawa. "Stabilization of calmodulin-dependent protein kinase II through the autoinhibitory domain." Journal of Biological Chemistry 270.5 (1995): 2163-2170.

Ji, Yong, et al. "Targeted inhibition of Ca2+/calmodulin-dependent protein kinase II in cardiac longitudinal sarcoplasmic reticulum results in decreased phospholamban phosphorylation at threonine 17." Journal of Biological Chemistry 278.27 (2003): 25063-25071.