MeOSuc-Ala-Ala-Pro-Val-AMC

Description:

A highly sensitive fluorogenic substrate for the assay of human neutrophil and porcine pancreatic elastases.

Sequence:

MONO-METHYL SUCCINATE--AAPV-AMC

General

References

Comments (0)

Name	MeOSuc-Ala-Ala-Pro-Val-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	MONO-METHYL SUCCINATE--AAPV-AMC
Three Letter Code	MONO-METHYL SUCCINATE-{Ala}{Ala}{Pro}{Val}-AMC
Molecular Weight	627.700
Application

Philips, Neena, et al. "Direct inhibition of elastase and matrixmetalloproteinases and stimulation of biosynthesis of fibrillar collagens, elastin, and fibrillins by xanthohumol." Journal of cosmetic science 61.2 (2010): 125-132.

Methot, Nathalie, et al. "In vivo inhibition of serine protease processing requires a high fractional inhibition of cathepsin C." Molecular pharmacology 73.6 (2008): 1857-1865.

Méthot, Nathalie, et al. "Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing." Journal of Biological Chemistry 282.29 (2007): 20836-20846.

Ivanov, Dmitri, et al. "A serpin from the gut bacterium Bifidobacterium longum inhibits eukaryotic elastase-like serine proteases." Journal of Biological Chemistry 281.25 (2006): 17246-17252.