IRAK - 1 (360 - 380); IRAK - 4 Peptide Substrate

Description:

This is a substrate peptide for Interleukin-1 Receptor-Associated Kinase (IRAK) 4. IRAK-4 phosphorylates IRAK-1 as a key step in regulation of inflammatory signaling pathways.

Sequence:

KKARFSRFAGSSPSQSSMVAR

General

References

Comments (0)

Name	IRAK - 1 (360 - 380); IRAK - 4 Peptide Substrate
Category	Enzyme Substrates and Inhibitors
One Letter Code	KKARFSRFAGSSPSQSSMVAR
Three Letter Code	{Lys}{Lys}{Ala}{Arg}{Phe}{Ser}{Arg}{Phe}{Ala}{Gly}{Ser}{Ser}{Pro}{Ser}{Gln}{Ser}{Ser}{Met}{Val}{Ala}{Arg}
Molecular Weight	2285.600
Application

Hekmat-Nejad, Mohammad, Terrence Cai, and David C. Swinney. "Steady-state kinetic characterization of kinase activity and requirements for Mg2+ of interleukin-1 receptor-associated kinase-4." Biochemistry 49.7 (2010): 1495-1506.