Calcineurin Substrate

Description:

The peptide is a fragment of the RII subunit of the cAMP-dependent protein kinase

Sequence:

DLDVPIPGRFDRRVSVAAE
  • General
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  • Name Calcineurin Substrate
    Category Enzyme Substrates and Inhibitors
    One Letter Code DLDVPIPGRFDRRVSVAAE
    Three Letter Code {Asp}{Leu}{Asp}{Val}{Pro}{Ile}{Pro}{Gly}{Arg}{Phe}{Asp}{Arg}{Arg}{Val}{Ser}{Val}{Ala}{Ala}{Glu} 
    Molecular Weight 2112.370
    Application
    Lemaitre, Florian, et al. "Pharmacokinetics and pharmacodynamics of tacrolimus in liver transplant recipients: inside the white blood cells." Clinical biochemistry 48.6 (2015): 406-411.
    Blanchet, Benoı̂t, et al. "Determination of serine/threonine protein phosphatase type 2B (PP2B) in lymphocytes by HPLC." Analytical biochemistry 312.1 (2003): 1-6.
    Namgaladze, Dmitry, H. Werner Hofer, and Volker Ullrich. "Redox control of calcineurin by targeting the binuclear Fe2+-Zn2+ center at the enzyme active site." Journal of Biological Chemistry 277.8 (2002): 5962-5969.
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