DABCYL-TNF-α-EDANS (-4 to +6) (human)

Description:

N/A

Sequence:

DABCYL-LAQAVRSSSR-EDANS
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  • Name DABCYL-TNF-α-EDANS (-4 to +6) (human)
    Category Enzyme Substrates and Inhibitors
    One Letter Code DABCYL-LAQAVRSSSR-EDANS
    Three Letter Code DABCYL-{Leu}{Ala}{Gln}{Ala}{Val}{Arg}{Ser}{Ser}{Ser}{Arg}-EDANS
    Molecular Weight 1573.800
    Application Alzheimer's DiseaseCancer ResearchInflammation Research
    Bacha, Usman, et al. "Identification of novel inhibitors of the SARS coronavirus main protease 3CLpro." Biochemistry 43.17 (2004): 4906-4912.
    Neumann, Ulf, et al. "Characterization of Mca-Lys-Pro-Leu-Gly-Leu-Dpa-Ala-Arg-NH2, a fluorogenic substrate with increased specificity constants for collagenases and tumor necrosis factor converting enzyme." Analytical biochemistry 328.2 (2004): 166-173.
    Becker, Bernhard F., et al. "Application of peptides containing the cleavage sequence of pro-TNFα in assessing TACE activity of whole cells." Biological chemistry 383.11 (2002): 1821-1826.
    Gearing, A. J. H., et al. "Processing of tumour necrosis factor-α precursor by metalloproteinases." Nature 370.6490 (1994): 555-557.
    Mohler, Kendall M., et al. "Protection against a lethal dose of endotoxin by an inhibitor of tumour necrosis factor processing." Nature 370.6486 (1994): 218-220.
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