Z-Leu-Leu-Arg-AMC

Description:

Fluorogenic substrate for cathepsin S.

Sequence:

CBZ-LLR-AMC

General

References

Comments (0)

Name	Z-Leu-Leu-Arg-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	CBZ-LLR-AMC
Three Letter Code	CBZ-{Leu}{Leu}{Arg}-AMC
Molecular Weight	691.830
Application

Pérez, Bianca, et al. "Toward the discovery of inhibitors of babesipain-1, a Babesia bigemina cysteine protease: in vitro evaluation, homology modeling and molecular docking studies." Journal of computer-aided molecular design 27.9 (2013): 823-835.

Martins, Tiago M., Virgílio E. do Rosário, and Ana Domingos. "Expression and characterization of the Babesia bigemina cysteine protease BbiCPL1." Acta tropica 121.1 (2012): 1-5.

Caldeira, Rubina L., et al. "Plasmodium chabaudi: Expression of active recombinant chabaupain-1 and localization studies in Anopheles sp." Experimental parasitology 122.2 (2009): 97-105.

Irie, Osamu, et al. "Discovery of orally bioavailable cathepsin S inhibitors for the reversal of neuropathic pain." Journal of medicinal chemistry 51.18 (2008): 5502-5505.