Z-Ala-Ala-Asn-AMC

Description:

standard substrate for legumain. Legumain may be a physiologic local regulator of human osteoclast (OCL) activity that can negatively modulate OCL.

Sequence:

CBZ-AAN-AMC

General

References

Comments (0)

Name	Z-Ala-Ala-Asn-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	CBZ-AAN-AMC
Three Letter Code	CBZ-{Ala}{Ala}{Asn}-AMC
Molecular Weight	565.580
Application

Qi, Qi, et al. "Blockade of asparagine endopeptidase inhibits cancer metastasis." Journal of medicinal chemistry 60.17 (2017): 7244-7255.

Berven, Lise, et al. "The polar high molecular weight fraction of the Agaricus blazei Murill extract, AndoSan™, reduces the activity of the tumor-associated protease, legumain, in RAW 264.7 cells." Journal of medicinal food 18.4 (2015): 429-438.

Hong, Jinhua, et al. "Exploring atomic defects in molybdenum disulphide monolayers." Nature communications 6.1 (2015): 1-8.