Z-Phe-His-Leu-OH

Description:

Substrate for angiotensin I-converting enzyme.

Sequence:

CBZ- FHL

General

References

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Name	Z-Phe-His-Leu-OH
Category	Enzyme Substrates and Inhibitors
One Letter Code	CBZ- FHL
Three Letter Code	CBZ-{Phe}{His}{Leu}
Molecular Weight	549.630
Application	Cardiovascular System & Diseases

Yates, Christopher J., et al. "Molecular and thermodynamic mechanisms of the chloride-dependent human angiotensin-I-converting enzyme (ACE)." Journal of Biological Chemistry289.3 (2014): 1798-1814.

Ocaranza, Maria Paz, et al. "Angiotensin-(1–9) reverses experimental hypertension and cardiovascular damage by inhibition of the angiotensin converting enzyme/Ang II axis." Journal of hypertension 32.4 (2014): 771-783.

Anthony, Colin S., et al. "The N Domain of Human Angiotensin-I-converting Enzyme THE ROLE OF N-GLYCOSYLATION AND THE CRYSTAL STRUCTURE IN COMPLEX WITH AN N DOMAIN-SPECIFIC PHOSPHINIC INHIBITOR, RXP407." Journal of Biological Chemistry 285.46 (2010): 35685-35693.

Le Corvoisier, Philippe, et al. "The cardiac renin–angiotensin system is responsible for high‐salt diet‐induced left ventricular hypertrophy in mice." European journal of heart failure 12.11 (2010): 1171-1178.