Boc-Gln-Arg-Arg-AMC

Description:

A substrate for the transmembrane serine protease hepsin

Sequence:

Boc-QRR-AMC

General

References

Comments (0)

Name	Boc-Gln-Arg-Arg-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	Boc-QRR-AMC
Three Letter Code	Boc-{Gln}{Arg}{Arg}-AMC
Molecular Weight	715.810
Application

Obiezu, Chistina V., et al. "Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins." Biological chemistry 387.6 (2006): 749-759.

Holyoak, Todd, et al. "Structural basis for differences in substrate selectivity in Kex2 and furin protein convertases." Biochemistry 43.9 (2004): 2412-2421.

Holyoak, Todd, et al. "2.4 Å resolution crystal structure of the prototypical hormone-processing protease Kex2 in complex with an Ala-Lys-Arg boronic acid inhibitor." Biochemistry 42.22 (2003): 6709-6718.

Kunii, Daisuke, et al. "Purification of liver serine protease which activates microsomal glutathione S-transferase: possible involvement of hepsin." Biological and Pharmaceutical Bulletin 29.5 (2006): 868-874.