Boc-Leu-Lys-Arg-AMC

Description:

A substrate for the Kex2 endoprotease

Sequence:

Boc-LKR-AMC

General

References

Comments (0)

Name	Boc-Leu-Lys-Arg-AMC
Category	Enzyme Substrates and Inhibitors
One Letter Code	Boc-LKR-AMC
Three Letter Code	Boc-{Leu}{Lys}{Arg}-AMC
Molecular Weight	672.830
Application

Méthot, Nathalie, et al. "Inhibition of the activation of multiple serine proteases with a cathepsin C inhibitor requires sustained exposure to prevent pro-enzyme processing." Journal of Biological Chemistry 282.29 (2007): 20836-20846.

Obiezu, Chistina V., et al. "Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins." Biological chemistry 387.6 (2006): 749-759.

Palmer, James T., et al. "Keto-1, 3, 4-oxadiazoles as cathepsin K inhibitors." Bioorganic & medicinal chemistry letters 16.11 (2006): 2909-2914.