Boc-Leu-Gly-Arg-AMC

Description:

A specific fluorogenic substrate for complement component C3/C5 convertases, coagulation factor Xa, and soybean trypsin-like enzyme.

Sequence:

Boc-LGR-AMC
  • General
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  • Name Boc-Leu-Gly-Arg-AMC
    Category Enzyme Substrates and Inhibitors
    One Letter Code Boc-LGR-AMC
    Three Letter Code Boc-{Leu}{Gly}{Arg}-AMC
    Molecular Weight 601.700
    Application Hematology
    Duncan, Renee C., et al. "Identification of a catalytic exosite for complement component C4 on the serine protease domain of C1s." The Journal of Immunology 189.5 (2012): 2365-2373.
    Beinrohr, László, et al. "Serpins and the complement system." Methods in enzymology. Vol. 499. Academic Press, 2011. 55-75.
    Dolečková, Kateřina, et al. "The functional expression and characterisation of a cysteine peptidase from the invasive stage of the neuropathogenic schistosome Trichobilharzia regenti." International journal for parasitology 39.2 (2009): 201-211.
    Kašný, M., et al. "Comparison of cysteine peptidase activities in Trichobilharzia regenti and Schistosoma mansoni cercariae." Parasitology 134.11 (2007): 1599-1609.
    Obiezu, Chistina V., et al. "Human kallikrein 4: enzymatic activity, inhibition, and degradation of extracellular matrix proteins." Biological chemistry 387.6 (2006): 749-759.
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