Boc-Ala-Ala-pNA

Description:

Boc-AA-pNA is cleaved by serine proteases.

Sequence:

Boc-.AA-p-Nitroanilide
  • General
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  • Name Boc-Ala-Ala-pNA
    Category Enzyme Substrates and Inhibitors
    One Letter Code Boc-.AA-p-Nitroanilide
    Three Letter Code Boc-{Ala}{Ala}-p-Nitroanilide
    Molecular Weight 380.400
    Application
    Brinen, Linda S., et al. "A target within the target: probing cruzain’s P1′ site to define structural determinants for the Chagas’ disease protease." Structure 8.8 (2000): 831-840.
    Bogyo, Matthew, et al. "Selective targeting of lysosomal cysteine proteases with radiolabeled electrophilic substrate analogs." Chemistry & biology 7.1 (2000): 27-38.
    Du, Xiaohui, et al. "Aryl ureas represent a new class of anti-trypanosomal agents." Chemistry & biology 7.9 (2000): 733-742.
    Healy, N., et al. "Detection of peptidases in Trypanosoma cruzi epimastigotes using chromogenic and fluorogenic substrates." Parasitology 104.2 (1992): 315-322.
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