Bz-Val-Gly-Arg-AMC

Description:

Bz-VGR-AMC is used for measuring the trypsin-like activity of the 20S proteasome

Sequence:

Benzoyl-VGR-AMC
  • General
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  • Name Bz-Val-Gly-Arg-AMC
    Category Enzyme Substrates and Inhibitors
    One Letter Code Benzoyl-VGR-AMC
    Three Letter Code Benzoyl-{Val}{Gly}{Arg}-AMC
    Molecular Weight 591.670
    Application
    Brehm, Anja, et al. "Additive loss-of-function proteasome subunit mutations in CANDLE/PRAAS patients promote type I IFN production." The Journal of clinical investigation 125.11 (2015): 4196-4211.
    Bianchi, Giada, et al. "The proteasome load versus capacity balance determines apoptotic sensitivity of multiple myeloma cells to proteasome inhibition." Blood, The Journal of the American Society of Hematology 113.13 (2009): 3040-3049.
    Scolari, G., et al. "Extraction and partial characterization of proteolytic activities from the cell surface of Lactobacillus helveticus Zuc2." Journal of dairy science 89.10 (2006): 3800-3809.
    Braun, Hannes A., et al. "Tripeptide mimetics inhibit the 20 S proteasome by covalent bonding to the active threonines." Journal of Biological Chemistry 280.31 (2005): 28394-28401.
    Meiners, Silke, et al. "Downregulation of matrix metalloproteinases and collagens and suppression of cardiac fibrosis by inhibition of the proteasome." Hypertension 44.4 (2004): 471-477.
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