H-Ala-Pro-AFC

Description:

Fluorogenic substrate for dipeptidyl peptidase IV (DPP IV) and Xaa-Pro dipeptidase.

Sequence:

AP-AFC

General

References

Comments (0)

Name	H-Ala-Pro-AFC
Category	Enzyme Substrates and Inhibitors
One Letter Code	AP-AFC
Three Letter Code	{Ala}{Pro}-AFC
Molecular Weight	397.350
Application	Hematology

Steven, Sebastian, et al. "Glucagon‐like peptide‐1 receptor signalling reduces microvascular thrombosis, nitro‐oxidative stress and platelet activation in endotoxaemic mice." British journal of pharmacology 174.12 (2017): 1620-1632.

Schnapp, Gisela, et al. "Comparative analysis of binding kinetics and thermodynamics of dipeptidyl peptidase-4 inhibitors and their relationship to structure." Journal of medicinal chemistry 59.16 (2016): 7466-7477.

Chen, Meihua, et al. "A whole-cell tumor vaccine modified to express fibroblast activation protein induces antitumor immunity against both tumor cells and cancer-associated fibroblasts." Scientific reports 5.1 (2015): 1-14.

Keane, Fiona M., et al. "Quantitation of fibroblast activation protein (FAP)-specific protease activity in mouse, baboon and human fluids and organs." FEBS open bio 4 (2014): 43-54.

Shah, Payal, et al. "The DPP-4 inhibitor linagliptin restores β-cell function and survival in human isolated islets through GLP-1 stabilization." The Journal of Clinical Endocrinology & Metabolism 98.7 (2013): E1163-E1172.

Kern, Matthias, et al. "Linagliptin improves insulin sensitivity and hepatic steatosis in diet-induced obesity." PloS one 7.6 (2012).