Ac-Lys-Gln-Leu-Arg-AFC

Description:

Ac-KQLR-AFC is the optimal substrate for human hepsin

Sequence:

Ac-KQLR-AFC

General

References

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Name	Ac-Lys-Gln-Leu-Arg-AFC
Category	Enzyme Substrates and Inhibitors
One Letter Code	Ac-KQLR-AFC
Three Letter Code	Acetylation-{Lys}{Gln}{Leu}{Arg}-AFC
Molecular Weight	796.850
Application	Cancer Research

Koschubs, Tobias, et al. "Allosteric antibody inhibition of human hepsin protease." Biochemical Journal 442.3 (2012): 483-494.

Herter, Sylvia, et al. "Hepatocyte growth factor is a preferred in vitro substrate for human hepsin, a membrane-anchored serine protease implicated in prostate and ovarian cancers." Biochemical Journal 390.1 (2005): 125-136.