FA-Ala-Arg-OH

Description:

Substrate for human plasma carboxypeptidase N and membrane-bound carboxypeptidase D.

Sequence:

3-(2-Furyl)acrylic acid- AR
  • General
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  • Name FA-Ala-Arg-OH
    Category Enzyme Substrates and Inhibitors
    One Letter Code 3-(2-Furyl)acrylic acid- AR
    Three Letter Code 3-(2-Furyl)acrylic acid-{Ala}{Arg}
    Molecular Weight 365.390
    Application
    Mueller-Ortiz, Stacey L., et al. "Targeted disruption of the gene encoding the murine small subunit of carboxypeptidase N (CPN1) causes susceptibility to C5a anaphylatoxin-mediated shock." The Journal of Immunology 182.10 (2009): 6533-6539.
    Deiteren, Kathleen, et al. "The role of the S1 binding site of carboxypeptidase M in substrate specificity and turn-over." Biochimica et Biophysica Acta (BBA)-Proteins and Proteomics 1774.2 (2007): 267-277.
    Do, Yee H., et al. "Inhibition of thrombin activatable fibrinolysis inhibitor by cysteine derivatives." Thrombosis research 116.3 (2005): 265-271.
    Hadkar, Vaishali, et al. "Carboxypeptidase-mediated enhancement of nitric oxide production in rat lungs and microvascular endothelial cells." American Journal of Physiology-Lung Cellular and Molecular Physiology 287.1 (2004): L35-L45.
    Nagashima, Mariko, et al. "An inhibitor of activated thrombin-activatable fibrinolysis inhibitor potentiates tissue-type plasminogen activator-induced thrombolysis in a rabbit jugular vein thrombolysis model." Thrombosis research 98.4 (2000): 333-342.
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