Pyr-Pro-Arg-pNA

Description:

Chromogenic substrate or the determination of kinetic constants of tryptase.

Sequence:

{pGLU}PR-p-Nitroanilide

General

References

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Name	Pyr-Pro-Arg-pNA
Category	Enzyme Substrates and Inhibitors
One Letter Code	{pGLU}PR-p-Nitroanilide
Three Letter Code	{pGLU}{Pro}{Arg}-p-Nitroanilide
Molecular Weight	502.530
Application	Hematology

Fjellström, Ola, et al. "Creating novel activated factor XI inhibitors through fragment based lead generation and structure aided drug design." PloS one 10.1 (2015).

Engel, R., et al. "Single‐chain factor XII exhibits activity when complexed to polyphosphate." Journal of Thrombosis and Haemostasis 12.9 (2014): 1513-1522.

Oh, Se-Woong, et al. "Tryptase inhibition blocks airway inflammation in a mouse asthma model." The Journal of Immunology 168.4 (2002): 1992-2000.