Endothelin 3 (human, rat)

Description:

This ET-3 is a member of a family of potent vasoconstrictors namely, Endothelin and Sarafotoxin. ET-3 is a less potent vasoconstrictor than ET-1.

Sequence:

CTCFTYKDKECVYYCHLDIIW (Disulfide bridge: 1 - 15, 3 - 11)

General

References

Comments (0)

Name	Endothelin 3 (human, rat)
Category	Endothelins and Related Peptides
One Letter Code	CTCFTYKDKECVYYCHLDIIW (Disulfide bridge: 1 - 15, 3 - 11)
Three Letter Code	{Cys}{Thr}{Cys}{Phe}{Thr}{Tyr}{Lys}{Asp}{Lys}{Glu}{Cys}{Val}{Tyr}{Tyr}{Cys}{His}{Leu}{Asp}{Ile}{Ile}{Trp} (Disulfide bridge: 1-15 and 3-11) (Disulfide bridge: 1 - 15, 3 - 11)
Molecular Weight	2643.100
Application	Cardiovascular System & Diseases

Yuan, Kuichang, et al. "Effects of endothelin family on ANP secretion." Peptides 82 (2016): 12-19.

Mangahas, Catherine R., et al. "Endothelin-1 induces CXCL1 and CXCL8 secretion in human melanoma cells." Journal of investigative dermatology 125.2 (2005): 307-311.

Satyamoorthy, Kapaettu, et al. "Constitutive mitogen-activated protein kinase activation in melanoma is mediated by both BRAF mutations and autocrine growth factor stimulation." Cancer research 63.4 (2003): 756-759.

Abdel-Sayed, Saad, et al. "Measurement of plasma endothelin-1 in experimental hypertension and in healthy subjects." American journal of hypertension 16.7 (2003): 515-521.

Jamal, Sumayah, and Robert J. Schneider. "UV-induction of keratinocyte endothelin-1 downregulates E-cadherin in melanocytes and melanoma cells." The Journal of clinical investigation 110.4 (2002): 443-452.