(Ala¹·³·¹¹·¹⁵)-Endothelin-1

Description:

Linear analog of ET-1 is a selective agonist for ET-B receptors.

Sequence:

ASASSLMDKEAVYFAHLDIIW

General

References

Comments (0)

Name	(Ala¹·³·¹¹·¹⁵)-Endothelin-1
Category	Endothelins and Related Peptides
One Letter Code	ASASSLMDKEAVYFAHLDIIW
Three Letter Code	{Ala}{Ser}{Ala}{Ser}{Ser}{Leu}{Met}{Asp}{Lys}{Glu}{Ala}{Val}{Tyr}{Phe}{Ala}{His}{Leu}{Asp}{Ile}{Ile}{Trp}
Molecular Weight	2367.710
Application	Cardiovascular System & Diseases

Compeer, Matthijs G., et al. "Endothelin-1 and-2: two amino acids matter." Life sciences 91.13-14 (2012): 607-612.

Meens, Merlijn JPMT, et al. "Stimuli of sensory-motor nerves terminate arterial contractile effects of endothelin-1 by CGRP and dissociation of ET-1/ETA-receptor complexes." PLoS One 5.6 (2010).

Nakamichi, Kyoko, et al. "Different distribution of endothelin receptor subtypes in pulmonary tissues revealed by the novel selective ligands BQ-123 and [Ala1, 3, 11, 15] ET-1." Biochemical and biophysical research communications 182.1 (1992): 144-150.

Bigaud, Marc, and John T. Pelton. "Discrimination between ETA‐and ETB‐receptor‐mediated effects of endothelin‐1 and [Ala1, 3, 11, 15] endothelin‐1 by BQ‐123 in the anaesthetized rat." British journal of pharmacology 107.4 (1992): 912-918.