Big Endothelin - 1 (1 - 38) (human)

Description:

Big Endothelin-1 (1-38) is precursor of endothelin 1.

Sequence:

CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS (Disulfide bridge: 1 - 15, 3 - 11)
  • General
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  • Name Big Endothelin - 1 (1 - 38) (human)
    Category Endothelins and Related Peptides
    One Letter Code CSCSSLMDKECVYFCHLDIIWVNTPEHVVPYGLGSPRS (Disulfide bridge: 1 - 15, 3 - 11)
    Three Letter Code {Cys}{Ser}{Cys}{Ser}{Ser}{Leu}{Met}{Asp}{Lys}{Glu}{Cys}{Val}{Tyr}{Phe}{Cys}{His}{Leu}{Asp}{Ile}{Ile}{Trp}{Val}{Asn}{Thr}{Pro}{Glu}{His}{Val}{Val}{Pro}{Tyr}{Gly}{Leu}{Gly}{Ser}{Pro}{Arg}{Ser} (Disulfide bridge: 1-15, 3-11) (Disulfide bridge: 1 - 15, 3 - 11)
    Molecular Weight 4283.000
    Application Cardiovascular System & Diseases
    Fecteau, Marie-Hélène, et al. "Endothelin-1 (1-31) is an intermediate in the production of endothelin-1 after big endothelin-1 administration in vivo." Hypertension 46.1 (2005): 87-92.
    Gurusankar, Roma, et al. "Correlation between saliva and plasma levels of endothelin isoforms ET-1, ET-2, and ET-3." International journal of peptides 2015 (2015).
    Kumarathasan, P., et al. "Applicability of a high-throughput shotgun plasma protein screening approach in understanding maternal biological pathways relevant to infant birth weight outcome." Journal of proteomics 100 (2014): 136-146.
    Karthikeyan, Subramanian, Premkumari Kumarathasan, and Renaud Vincent. "Data mining of plasma peptide chromatograms for biomarkers of air contaminant exposures." Proteome science 6.1 (2008): 6.
    Abdel-Sayed, Saad, et al. "Measurement of plasma endothelin-1 in experimental hypertension and in healthy subjects." American journal of hypertension 16.7 (2003): 515-521.
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