Endothelin 1 (human, porcine)

Description:

ET-1 is a potent vasoconstrictor peptide derived from endothelial cells.

Sequence:

CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: 1 - 15, 3 - 11)
  • General
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  • Name Endothelin 1 (human, porcine)
    Category Endothelins and Related Peptides
    One Letter Code CSCSSLMDKECVYFCHLDIIW (Disulfide bridge: 1 - 15, 3 - 11)
    Three Letter Code {Cys}{Ser}{Cys}{Ser}{Ser}{Leu}{Met}{Asp}{Lys}{Glu}{Cys}{Val}{Tyr}{Phe}{Cys}{His}{Leu}{Asp}{Ile}{Ile}{Trp} (Disulfide bridge: 1-15, 3-11) (Disulfide bridge: 1 - 15, 3 - 11)
    Molecular Weight 2492.000
    Application Cardiovascular System & Diseases
    Moody, Terry W., et al. "Endothelin causes transactivation of the EGFR and HER2 in non-small cell lung cancer cells." Peptides 90 (2017): 90-99.
    Meyers, Eric, et al. "The supination assessment task: An automated method for quantifying forelimb rotational function in rats." Journal of neuroscience methods 266 (2016): 11-20.
    Akashi, Kengo, et al. "Knockout of endothelin type B receptor signaling attenuates bleomycin-induced skin sclerosis in mice." Arthritis research & therapy 18.1 (2016): 113.
    Yuan, Kuichang, et al. "Effects of endothelin family on ANP secretion." Peptides 82 (2016): 12-19.
    Leurgans, Thomas M., et al. "Endothelin‐1 shifts the mediator of bradykinin‐induced relaxation from NO to H2O2 in resistance arteries from patients with cardiovascular disease." British journal of pharmacology 173.10 (2016): 1653-1664.
    Ramseyer, Vanesa D., et al. "Angiotensin II-mediated hypertension impairs nitric oxide-induced NKCC2 inhibition in thick ascending limbs." American Journal of Physiology-Renal Physiology 310.8 (2016): F748-F754.
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