Melanotropin-Potentiating Factor

Description:

The fragment KKGE could potentiate the melanotropic activity of melanocyte-stimulating hormones (MSH)

Sequence:

KKGE
  • General
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  • Name Melanotropin-Potentiating Factor
    Category Endorphins, MPF, Neoendorphins
    One Letter Code KKGE
    Three Letter Code {Lys}{Lys}{Gly}{Glu} 
    Molecular Weight 460.530
    Application Opioid Research
    Owen, D. B., et al. "Trophic effects of melanotropin-potentiating factor (MPF) on cultures of cells of the central nervous system." Peptides 18.7 (1997): 1015-1021.
    Goverde, H. J. M., G. J. Pesman, and A. G. H. Smals. "The melanotropin potentiating factor and β-endorphin do not modulate the α-melanotropinor adrencocorticotropin-induced corticosteroidogenesis in purified isolated rat adrenal cells." Neuropeptides 12.3 (1988): 125-130.
    Morley, J. S., and D. M. Ensor. "Neurotrophic effects of beta endorphin C-terminal tetrapeptide (MPF)." Neuropeptides 8.1 (1986): 45-49.
    Richter, W. O., and P. Schwandt. "Melanotropin potentiating factor inhibits lipolytic activity of β-lipotropin but not of melanocyte stimulating hormones." Neuropeptides 7.1 (1986): 73-77.
    Logan, Ann, et al. "Melanotrophin-potentiating factor (MPF) potentiates MSH-induced melanogenesis in hair follicle melanocytes." Peptides 2.2 (1981): 121-123.
    Carter, R. J., S. A. M. Shuster, and J. S. Morley. "Melanotropin potentiating factor is the C-terminal tetrapeptide of human β-lipotropin." Nature 279.5708 (1979): 74-75.
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