(D-Arg²,Lys⁴)-Dermorphin (1-4), amide

Description:

DALDA (YrFK-NH₂) serve as a research tool to study the basic opioid pharmacology and specifically peripheral µ-receptor interactions.

Sequence:

Y{D-Arg}FK-NH₂

General

References

Comments (0)

Name	(D-Arg²,Lys⁴)-Dermorphin (1-4), amide
Category	Deltorphins and Dermorphins
One Letter Code	Y{D-Arg}FK-NH₂
Three Letter Code	{Tyr}{D-Arg}{Phe}{Lys}-NH₂
Molecular Weight	611.750
Application	Opioid Research

Shah, Lipa, Florence Gattacceca, and Mansoor M. Amiji. "CNS delivery and pharmacokinetic evaluations of DALDA analgesic peptide analog administered in Nano-sized oil-in-water emulsion formulation." Pharmaceutical research 31.5 (2014): 1315-1324.

Zimmerman, Dennis M., and J. David Leander. "Selective opioid receptor agonists and antagonists: research tools and potential therapeutic agents." Journal of medicinal chemistry 33.3 (1990): 895-902.

Schiller, Peter W., et al. "Dermorphin analogs carrying an increased positive net charge in their" message" domain display extremely high. mu.-opioid receptor selectivity." Journal of medicinal chemistry 32.3 (1989): 698-703.