C - Peptide - 2 (rat)

Description:

This rat C-peptide-2 differs from the active human C-peptide by several amino acids.C-Peptide 2 (rat) is shown to be effective in augmenting glucose utilization in streptozotocin diabetic rats.

Sequence:

EVEDPQVAQLELGGGPGAGDLQTLALEVARQ

General

References

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Name	C - Peptide - 2 (rat)
Category	C-Peptides
One Letter Code	EVEDPQVAQLELGGGPGAGDLQTLALEVARQ
Three Letter Code	{Glu}{Val}{Glu}{Asp}{Pro}{Gln}{Val}{Ala}{Gln}{Leu}{Glu}{Leu}{Gly}{Gly}{Gly}{Pro}{Gly}{Ala}{Gly}{Asp}{Leu}{Gln}{Thr}{Leu}{Ala}{Leu}{Glu}{Val}{Ala}{Arg}{Gln}
Molecular Weight	3161.500
Application	Diabetes

Tsimaratos, M., et al. "C-peptide stimulates Na+, K+-ATPase activity via PKC alpha in rat medullary thick ascending limb." Diabetologia 46.1 (2003): 124-131.

Kamiya, Hideki, et al. "C-Peptide reverses nociceptive neuropathy in type 1 diabetes." Diabetes 55.12 (2006): 3581-3587.

Sato, Y., et al. "C-peptide fragments stimulate glucose utilization in diabetic rats." Cellular and Molecular Life Sciences CMLS 61.6 (2004): 727-732.

Tsimaratos, M., et al. "C-peptide stimulates Na+, K+-ATPase activity via PKC alpha in rat medullary thick ascending limb." Diabetologia 46.1 (2003): 124-131.