C - peptide (57 - 87) (human)

Description:

C-peptide is cleaved from proinsulin, stored in secretory granules, and eventually released into the bloodstream in amounts equimolar with those of insulin.C-peptide administration in type 1 diabetes patients, who lack the peptide, alleviates the diabetes-induced renal and nerve dysfunctions

Sequence:

EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ

General

References

Comments (0)

Name	C - peptide (57 - 87) (human)
Category	C-Peptides
One Letter Code	EAEDLQVGQVELGGGPGAGSLQPLALEGSLQ
Three Letter Code	{Glu}{Ala}{Glu}{Asp}{Leu}{Gln}{Val}{Gly}{Gln}{Val}{Glu}{Leu}{Gly}{Gly}{Gly}{Pro}{Gly}{Ala}{Gly}{Ser}{Leu}{Gln}{Pro}{Leu}{Ala}{Leu}{Glu}{Gly}{Ser}{Leu}{Gln}
Molecular Weight	3020.300
Application	Diabetes

Ahangarpour, Akram, Ali Akbar Oroojan, and Maryam Radan. "Effect of aqueous and hydro-alcoholic extracts of lettuce (Lactuca sativa) seed on testosterone level and spermatogenesis in NMRI mice." Iranian journal of reproductive medicine 12.1 (2014): 65.

Sobhi, Hamid Reza, et al. "Generic approach for the sensitive absolute quantification of large undigested peptides in plasma using a particular liquid chromatography–mass spectrometry setup." Journal of Chromatography A 1218.47 (2011): 8536-8543.

Rodríguez Cabaleiro, Diego, et al. "Feasibility of standardization of serum c-peptide immunoassays with isotope-dilution liquid chromatography–tandem mass spectrometry." Clinical chemistry 52.6 (2006): 1193-1196.

Palmer, Jerry P., et al. "C-peptide is the appropriate outcome measure for type 1 diabetes clinical trials to preserve β-cell function: report of an ADA workshop, 21–22 October 2001." Diabetes 53.1 (2004): 250-264.