CRF (6-33) (human, rat)

Description:

This CRF fragment is used to study Alzheimer's disease (AD).

Sequence:

ISLDLTFHLLREVLEMARAEQLAQQAHS

General

References

Comments (0)

Name	CRF (6-33) (human, rat)
Category	Corticotropin-Releasing Factor (CRF) and Analogs
One Letter Code	ISLDLTFHLLREVLEMARAEQLAQQAHS
Three Letter Code	{Ile}{Ser}{Leu}{Asp}{Leu}{Thr}{Phe}{His}{Leu}{Leu}{Arg}{Glu}{Val}{Leu}{Glu}{Met}{Ala}{Arg}{Ala}{Glu}{Gln}{Leu}{Ala}{Gln}{Gln}{Ala}{His}{Ser}
Molecular Weight	3220.700
Application	Alzheimer's Disease

Li, Kun, et al. "A cortical circuit for sexually dimorphic oxytocin-dependent anxiety behaviors." Cell 167.1 (2016): 60-72.

Wanat, M. J., et al. "Corticotropin‐releasing factor increases mouse ventral tegmental area dopamine neuron firing through a protein kinase C‐dependent enhancement of Ih." The Journal of physiology 586.8 (2008): 2157-2170.

Behan, Dominic P., et al. "Displacement of corticotropin releasing factor from its binding protein as a possible treatment for Alzheimer's disease." Nature 378.6554 (1995): 284-287.

Sutton, STEVEN W., et al. "Ligand requirements of the human corticotropin-releasing factor-binding protein." Endocrinology 136.3 (1995): 1097-1102.