α-Helical CRF (9-41)

Description:

CRF antagonist.

Sequence:

DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH₂

General

References

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Name	α-Helical CRF (9-41)
Category	Corticotropin-Releasing Factor (CRF) and Analogs
One Letter Code	DLTFHLLREMLEMAKAEQEAEQAALNRLLLEEA-NH₂
Three Letter Code	{Asp}{Leu}{Thr}{Phe}{His}{Leu}{Leu}{Arg}{Glu}{Met}{Leu}{Glu}{Met}{Ala}{Lys}{Ala}{Glu}{Gln}{Glu}{Ala}{Glu}{Gln}{Ala}{Ala}{Leu}{Asn}{Arg}{Leu}{Leu}{Leu}{Glu}{Glu}{Ala}-NH₂
Molecular Weight	3826.410
Application	Pituitary & Hypothalamic Hormones

Park, Hyo‐Jin, et al. "The stress response neuropeptide CRF increases amyloid‐β production by regulating γ‐secretase activity." The EMBO journal 34.12 (2015): 1674-1686.

Jászberényi, Miklós, et al. "The actions of neuropeptide SF on the hypothalamic–pituitary–adrenal axis and behavior in rats." Regulatory peptides 188 (2014): 46-51.

Miragaya, Joanna R., and Ruth BS Harris. "Antagonism of corticotrophin-releasing factor receptors in the fourth ventricle modifies responses to mild but not restraint stress." American Journal of Physiology-Regulatory, Integrative and Comparative Physiology 295.2 (2008): R404-R416.

Jaszberenyi, M., et al. "Mediation of the behavioral, endocrine and thermoregulatory actions of ghrelin." Hormones and behavior 50.2 (2006): 266-273.

Herringa, Ryan J., et al. "Corticotropin-releasing factor (CRF), but not corticosterone, increases basolateral amygdala CRF-binding protein." Brain research 1083.1 (2006): 21-28.