Angiotensin (1-12) (human)

Description:

Angiotensin 1-12 is cleaved in human cardiac tissue by chymase yielding angiotensin II.

Sequence:

DRVYIHPFHLVI

General

References

Comments (0)

Name	Angiotensin (1-12) (human)
Category	Angiotensins and Related Peptides
One Letter Code	DRVYIHPFHLVI
Three Letter Code	{Asp}{Arg}{Val}{Tyr}{Ile}{His}{Pro}{Phe}{His}{Leu}{Val}{Ile}
Molecular Weight	1508.790
Application	Cardiovascular System & Diseases

Bujak-Gizycka, B., et al. "Angiotensinogen metabolism in rat aorta: robust formation of proangiotensin-12." Journal of Physiology and Pharmacology 61.6 (2010): 679.

Trask, Aaron J., et al. "Angiotensin-(1-12) is an alternate substrate for angiotensin peptide production in the heart." American Journal of Physiology-Heart and Circulatory Physiology 294.5 (2008): H2242-H2247.

Nagata, Sayaka, et al. "Isolation and identification of proangiotensin-12, a possible component of the renin–angiotensin system." Biochemical and biophysical research communications 350.4 (2006): 1026-1031.