Chimeric Rabies Virus Glycoprotein Fragment (RVG - 9R)

Description:

This Chimeric rabies virus glycoprotein fragment peptide (RVG-9R peptide) is able to bind and transduce siRNA to neuronal cells in vitro, resulting in efficient gene silencing.

Sequence:

YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR
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  • Name Chimeric Rabies Virus Glycoprotein Fragment (RVG - 9R)
    Category Cell Permeable Peptides (CPP) / Drug Delivery Peptides
    One Letter Code YTIWMPENPRPGTPCDIFTNSRGKRASNGGGGRRRRRRRRR
    Three Letter Code {Tyr}{Thr}{Ile}{Trp}{Met}{Pro}{Glu}{Asn}{Pro}{Arg}{Pro}{Gly}{Thr}{Pro}{Cys}{Asp}{Ile}{Phe}{Thr}{Asn}{Ser}{Arg}{Gly}{Lys}{Arg}{Ala}{Ser}{Asn}{Gly}{Gly}{Gly}{Gly}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}
    Molecular Weight 4843.500
    Application Cell-permeable Peptides
    Kumar, Priti, et al. "Transvascular delivery of small interfering RNA to the central nervous system." Nature 448.7149 (2007): 39-43.
    Ye, Chunting, et al. "Silencing early viral replication in macrophages and dendritic cells effectively suppresses flavivirus encephalitis." PLoS One 6.3 (2011).
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