Tat - Beclin - 1

Description:

Beclin-1 peptide is the HIV-1 Nef binding portion of full-length human Beclin-1 protein (amino acids 267-299). Beclin-1 protein is an autophagy inducing agent that may trigger cellular adaptation, survival or cell death. When conjugated to the cell-permeable peptide, it can successfully enter cells and induce autophagy. RELATED PRODUCTS:Beclin-1, Cat# 65466Tat-Beclin-1, scrambled, Cat# 65468

Sequence:

YGRKKRRQRRRGGTNVFNATFEIWHDGEFGT

General

References

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Name	Tat - Beclin - 1
Category	Cell Permeable Peptides (CPP) / Drug Delivery Peptides
One Letter Code	YGRKKRRQRRRGGTNVFNATFEIWHDGEFGT
Three Letter Code	{Tyr}{Gly}{Arg}{Lys}{Lys}{Arg}{Arg}{Gln}{Arg}{Arg}{Arg}{Gly}{Gly}{Thr}{Asn}{Val}{Phe}{Asn}{Ala}{Thr}{Phe}{Glu}{Ile}{Trp}{His}{Asp}{Gly}{Glu}{Phe}{Gly}{Thr}
Molecular Weight	3741.100
Application	Cell-permeable Peptides

Shoji-Kawata, Sanae, et al. "Identification of a candidate therapeutic autophagy-inducing peptide." Nature 494.7436 (2013): 201-206.

Marquez, Rebecca T., and Liang Xu. "Bcl-2: Beclin 1 complex: multiple, mechanisms regulating autophagy/apoptosis toggle switch." American journal of cancer research 2.2 (2012): 214.