KALA Amphipathic Peptide

Description:

KALA is a cationic amphipathic cell-penetrating peptide (CPP) and is able to bind to DNA. It can be used as a DNA transfection reagent.

Sequence:

WEAKLAKALAKALAKHLAKALAKALKACEA

General

References

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Name	KALA Amphipathic Peptide
Category	Cell Permeable Peptides (CPP) / Drug Delivery Peptides
One Letter Code	WEAKLAKALAKALAKHLAKALAKALKACEA
Three Letter Code	{Trp}{Glu}{Ala}{Lys}{Leu}{Ala}{Lys}{Ala}{Leu}{Ala}{Lys}{Ala}{Leu}{Ala}{Lys}{His}{Leu}{Ala}{Lys}{Ala}{Leu}{Ala}{Lys}{Ala}{Leu}{Lys}{Ala}{Cys}{Glu}{Ala}
Molecular Weight	3131.800
Application	Cell-permeable Peptides

Nasrollahi, Saman A., et al. "Cell‐penetrating peptides as a novel transdermal drug delivery system." Chemical biology & drug design 80.5 (2012): 639-646.

Wyman, Tara B., et al. "Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers." Biochemistry 36.10 (1997): 3008-3017.

Han, Junghee, Mijung Lim, and Young Il Yeom. "Receptor-mediated gene transfer to cells of hepatic origin by galactosylated albumin-polylysine complexes." Biological and Pharmaceutical Bulletin 22.8 (1999): 836-840.

Wyman, Tara B., et al. "Design, synthesis, and characterization of a cationic peptide that binds to nucleic acids and permeabilizes bilayers." Biochemistry 36.10 (1997): 3008-3017.