Buforin

Description:

The 21 amino acid peptide, also referred to as Buforin II peptide, has been shown to possess anti-microbial activity by penetrating bacteria and inhibiting cellular functions.

Sequence:

TRSSRAGLQFPVGRVHRLLRK
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  • Name Buforin
    Category Cell Permeable Peptides (CPP) / Drug Delivery Peptides
    One Letter Code TRSSRAGLQFPVGRVHRLLRK
    Three Letter Code {Thr}{Arg}{Ser}{Ser}{Arg}{Ala}{Gly}{Leu}{Gln}{Phe}{Pro}{Val}{Gly}{Arg}{Val}{His}{Arg}{Leu}{Leu}{Arg}{Lys
    Molecular Weight 2434.900
    Application
    Lan, Yun, et al. "Structural contributions to the intracellular targeting strategies of antimicrobial peptides." Biochimica et Biophysica Acta (BBA)-Biomembranes 1798.10 (2010): 1934-1943.
    Bartz, René, et al. "Effective siRNA delivery and target mRNA degradation using an amphipathic peptide to facilitate pH-dependent endosomal escape." Biochemical Journal 435.2 (2011): 475-487.
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