H-Arg-Arg-Arg-Arg-Arg-Arg-OH

Description:

Six arginines is the minimum number of residues required for obtaining a polycationic peptide which can effectively penetrate cells.

Sequence:

RRRRRR

General

References

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Name	H-Arg-Arg-Arg-Arg-Arg-Arg-OH
Category	Cell Permeable Peptides (CPP) / Drug Delivery Peptides
One Letter Code	RRRRRR
Three Letter Code	{Arg}{Arg}{Arg}{Arg}{Arg}{Arg}
Molecular Weight	955.140
Application	Cell-permeable Peptides

Hitz, Thomas, et al. "Interaction of α-and β-oligoarginine-acids and amides with anionic lipid vesicles: a mechanistic and thermodynamic study." Biochemistry 45.18 (2006): 5817-5829.

Perret, Florent, et al. "Anionic fullerenes, calixarenes, coronenes, and pyrenes as activators of oligo/polyarginines in model membranes and live cells." Journal of the American Chemical Society 127.4 (2005): 1114-1115.

Lee, Youngmi, et al. "Improved planar amperometric nitric oxide sensor based on platinized platinum anode. 2. Direct real-time measurement of NO generated from porcine kidney slices in the presence of L-arginine, L-arginine polymers, and protamine." Analytical chemistry 76.3 (2004): 545-551.

Mitchell, Dennis J., et al. "Polyarginine enters cells more efficiently than other polycationic homopolymers." The Journal of Peptide Research 56.5 (2000): 318-325.